I really don't know about tunings in a way that I could tell you which one sounds better or otherwise. But as far as tone goes, absolutely it evokes a different feeling or emotion. I've mentioned before in other discussions I enjoy the LoFi genre that's been prevalent as relax/study music. There's a dissonant tone using pitch shifters and detuners, as well as bits of reverb, echo, etc. That music puts me in a state of peace where I can do things like draw. Like check out
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As far as what the electric guitar is mainly used for, and why all of us are drawn to this school, I lean more towards the hard rock/ alt metal areas. The tones used speak to my soul. The distortion feels turned down so the fuzz is still there, but there's a clarity to the screaming sound of the guitar. It makes me feel alive.