Since I work from home (telecommute) full time, it is absolutely mandatory that I have a room in the house that is only mine, 24 hours a day (I used to manage a Production Server Support team, which really was 24/7 on-call. Things are quieter now, but still…).
So that room has my work computer, and my personal computer, which is used for everything else – gaming, bills, internet, recording studio; everything. The guitars are all hung on the walls (no room left, but it’s not a huge room), and the rack and speaker for my AxeFX are here, on the floor, connected to the computer at all times.
In all of my current videos (not the one from the 90s, I mean), the guitar is recorded direct from the Axe into the video through the computer. Most of the time, I don’t even have the speaker hooked up – I just use headphones so the family is not inconvenienced.